⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177574 | 1.00 | — | — | |
| SCHEMBL11578112 | 0.83 | TSHR (0.39) | — | |
| SCHEMBL11578116 | 0.83 | TSHR (0.39) | — | |
| SCHEMBL26157990 | 0.81 | TRPA1 (0.37) | — | |
| SCHEMBL1782035 | 0.80 | TRPA1 (0.40) | — | |
| SCHEMBL1782036 | 0.80 | TRPA1 (0.40) | — | |
| SCHEMBL29455132 | 0.78 | TRPA1 (0.34) | — | |
| SCHEMBL1782794 | 0.78 | — | — | |
| SCHEMBL13853338 | 0.78 | — | — | |
| SCHEMBL1782793 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386538-B1 | N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | SHOWA DENKO KK (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8697912-B2 | N-(1-hydroxyethyl) carboxamide compound and process for producing same | SHOWA DENKO K.K. (JP) | 2014-04-15 | — | — | US | disclosed |
| CN-102272093-A | N-(1-hydroxyethyl)carboxamide compound and process for producing same | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110294974-A1 | N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | SHOWA DENKO K.K. (JP) | 2011-12-01 | — | — | US | disclosed |
| EP-2386538-A1 | N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | Showa Denko K.K. (JP) | 2011-11-16 | — | — | EP | disclosed |
| EP-0196708-B1 | PROCESS FOR THE PREPARATION OF 2-(HYDROXYALKYL)ACRYLIC COMPOUNDS | STAMICARBON B.V. (NL) | 1989-08-23 | — | — | EP | disclosed |
| US-4820858-A | Process for the preparation of 2-(hydroxyalkyl)acrylic compounds | STAMICARBON B.V. (NL) | 1989-04-11 | — | — | US | disclosed |
| EP-0196708-A1 | Process for the preparation of 2-(hydroxyalkyl)acrylic compounds | STAMICARBON B.V. (NL) | 1986-10-08 | — | — | EP | disclosed |