Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776891 | 1.00 | KLK7 (0.44) | KLK7KLK5HCRTR2PSEN1PSEN2 | |
| SCHEMBL2914271 | 0.89 | BCHE (0.43) | BCHEACHEAGTR2 | |
| SCHEMBL9547939 | 0.83 | KLK7 (0.44) | KLK7KLK5HCRTR2PSEN1PSEN2 | |
| SCHEMBL14763101 | 0.81 | KLK7 (0.47) | KLK7KLK5PSEN1PSEN2APH1B | |
| SCHEMBL14762446 | 0.81 | KLK7 (0.47) | KLK7KLK5PSEN1PSEN2APH1B | |
| SCHEMBL5465296 | 0.80 | SMN1; SMN2 (0.46) | KLK7KLK5HCRTR2SMN1; SMN2NPC1 | |
| SCHEMBL1776054 | 0.80 | GJB2 (0.42) | — | |
| SCHEMBL1778348 | 0.80 | GJB2 (0.42) | — | |
| SCHEMBL31420651 | 0.79 | KLK7 (0.46) | KLK7KLK5HCRTR2PSEN1PSEN2 | |
| SCHEMBL1777167 | 0.78 | PTPN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943584-B2 | Medicinal composition containing diabetes remedy | SANKYO COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |