Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17884 | 0.80 | PER2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL17279 | 0.79 | PER2 (0.31) | — | |
| SCHEMBL26628972 | 0.75 | CXCR4 (0.32) | — | |
| SCHEMBL17759 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL17306 | 0.73 | — | — | |
| SCHEMBL12473958 | 0.71 | CA1 (0.33) | CA1CA12CA2CA14 | |
| SCHEMBL10041484 | 0.69 | CA1 (0.43) | CA1CA12CA2CA14 | |
| SCHEMBL16261610 | 0.69 | CA1 (0.46) | CA1CA12CA2CA14 | |
| SCHEMBL16908265 | 0.69 | PARP1 (0.33) | — | |
| SCHEMBL20742418 | 0.69 | PARP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609081-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | Amgen Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |