SCHEMBL17761306

SCHEMBL17761306

NC(=O)CC1(c2ccc(Cl)c(Cl)c2)CCC1

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 19/20 0.64
SLC6A4 P31645 17/20 0.64
SLC6A2 P23975 10/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17761317 0.97 SLC6A3 (0.64) SLC6A3SLC6A4SLC6A2
SCHEMBL5086399 0.95 SLC6A3 (0.65) SLC6A3SLC6A4SLC6A2
SCHEMBL17761229 0.94 SLC6A3 (0.55) SLC6A3SLC6A4SLC6A2
SCHEMBL625149 0.86 SLC6A4 (0.61) SLC6A3SLC6A4SLC6A2
SCHEMBL12836587 0.82 SLC6A4 (0.54) SLC6A3SLC6A4SLC6A2
SCHEMBL11107936 0.82 SLC6A3 (0.56) SLC6A3SLC6A4SLC6A2
SCHEMBL17761234 0.80 SLC6A4 (0.59) SLC6A3SLC6A4SLC6A2
Hydrochloric Acid SCHEMBL15863091 0.80 SLC6A4 (0.62) SLC6A3SLC6A4SLC6A2
SCHEMBL5084070 0.80 SLC6A4 (0.60) SLC6A3SLC6A4SLC6A2
SCHEMBL12836588 0.79 SLC6A4 (0.59) SLC6A3SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210130285-A1 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS AURIMMED PHARMA, INC. 2021-05-06 US disclosed
US-10793515-B2 Compounds advantageous in the treatment of central nervous system diseases and disorders AURIMMED PHARMA, INC. (US) 2020-10-06 US disclosed
US-20160137592-A1 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS AURIMMED PHARMA, INC. 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210130285-A1 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS SMN1; SMN2, HDAC6, HDAC3 SLC6A3 167/4885SLC6A4 288/4885SLC6A2 278/4885
US-20160137592-A1 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS SMN1; SMN2, HDAC6, HDAC3 SLC6A3 167/4885SLC6A4 288/4885SLC6A2 278/4885
US-10793515-B2 Compounds advantageous in the treatment of central nervous system diseases and disorders SMN1; SMN2, HDAC6, CTSA SLC6A3 163/4885SLC6A4 305/4885SLC6A2 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.