Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 15/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1774071 | 0.99 | GUSB (0.42) | GUSBHTR2CHTR6 | |
| SCHEMBL1776567 | 0.89 | GUSB (0.42) | GUSBHTR6 | |
| Hydrochloric Acid SCHEMBL1775412 | 0.89 | GUSB (0.41) | GUSBHTR6 | |
| SCHEMBL1777263 | 0.86 | HTR2C (0.42) | GUSBHTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL1774866 | 0.85 | HTR2C (0.41) | GUSBHTR2CHTR6 | |
| SCHEMBL1776724 | 0.82 | GUSB (0.57) | GUSBHTR6 | |
| Hydrochloric Acid SCHEMBL1776626 | 0.81 | GUSB (0.56) | GUSBHTR6 | |
| SCHEMBL1776023 | 0.81 | HTR2C (0.43) | HTR2CHTR6 | |
| SCHEMBL1775721 | 0.80 | GUSB (0.46) | GUSBHTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL1776078 | 0.80 | HTR2C (0.42) | HTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |