Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464533 | 0.89 | CYP1A1 (0.50) | CYP1A1AKT1KDM4EALDH1A1MAPT | |
| SCHEMBL17762892 | 0.86 | CYP1A1 (0.49) | CYP1A1AKT1KDM4EALDH1A1MAPT | |
| SCHEMBL16335258 | 0.85 | ALDH1A1 (0.50) | CYP1A1KDM4EALDH1A1MAPTMAOB | |
| SCHEMBL16335137 | 0.79 | KDM4E (0.39) | CYP1A1KDM4EALDH1A1HPGDATM | |
| SCHEMBL16335175 | 0.79 | KDM4E (0.51) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL17762898 | 0.78 | CYP1A1 (0.35) | CYP1A1AKT1KDM4EALDH1A1MAPT | |
| SCHEMBL19464539 | 0.73 | CYP1A1 (0.51) | CYP1A1AKT1KDM4EALDH1A1MAPT | |
| SCHEMBL11369382 | 0.72 | KDM4E (0.68) | CYP1A1AKT1KDM4EALDH1A1MAPT | |
| SCHEMBL10237805 | 0.71 | CYP1A1 (0.49) | CYP1A1AKT1KDM4EALDH1A1MAPT | |
| SCHEMBL31260293 | 0.70 | ALDH1A1 (0.57) | KDM4EALDH1A1MAPTMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137659-A1 | CHROMANE AND CHROMENE DERIVATIVES AND THEIR USE AS CRAC MODULATORS | LUPIN LIMITED (IN) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137659-A1 | CHROMANE AND CHROMENE DERIVATIVES AND THEIR USE AS CRAC MODULATORS | ORAI1, RYR2, RYR1 | CYP1A1 440/4885AKT1 1391/4885KDM4E 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.