Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.58 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539170 | 1.00 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL1539162 | 1.00 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL12512841 | 1.00 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL1539235 | 1.00 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL3868757 | 1.00 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL1539192 | 1.00 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL1539207 | 0.97 | ALDH1A1 (0.55) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL1539287 | 0.97 | ALDH1A1 (0.55) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL1774941 | 0.97 | ALDH1A1 (0.55) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL1539175 | 0.95 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943559-B2 | Cyclopropanated macrocyclic ketones and lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-7943560-B2 | Cyclopropanated macrocyclic ketones and lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090087402-A1 | Cyclopropanated Macrocyclic Ketones and Lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-04-02 | — | — | US | disclosed |
| US-20090081150-A1 | CYCLOPROPANATED MACROCYCLIC KETONES AND LACTONES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-03-26 | — | — | US | disclosed |
| US-7485668-B2 | Cyclopropanated macrocyclic ketones and lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-7482380-B2 | Cyclopropanated macrocyclic ketones and lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20070142253-A1 | Cyclopropanated Macrocyclic Ketones and Lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-06-21 | — | — | US | disclosed |
| US-7189881-B2 | Cyclopropanated macrocyclic ketones and lactones | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-20060234883-A1 | For example, bicyclo[13.1.0]hexadecan-4-one; use in creating fragrances and scents in items such as perfumes, colognes and personal care products | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2006-10-19 | — | — | US | disclosed |
| US-20060234885-A1 | Cyclopropanated macrocyclic ketones and lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142253-A1 | Cyclopropanated Macrocyclic Ketones and Lactones | CBR3, CBR1, DCXR | TRIM24 3472/4885TRIM33 3982/4885ALDH1A1 651/4885 |
| US-20060234883-A1 | For example, bicyclo[13.1.0]hexadecan-4-one; use in creating fragrances and scents in items such as perfumes, colognes and personal care products | COL14A1, CCR4, PAOX | TRIM24 3381/4885TRIM33 4734/4885ALDH1A1 1593/4885 |
| US-20090087402-A1 | Cyclopropanated Macrocyclic Ketones and Lactones | CBR3, CBR1, DCXR | TRIM24 3827/4885TRIM33 3831/4885ALDH1A1 648/4885 |
| US-20090081150-A1 | CYCLOPROPANATED MACROCYCLIC KETONES AND LACTONES | CBR3, CBR1, DCXR | TRIM24 3827/4885TRIM33 3831/4885ALDH1A1 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.