Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 19/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099188 | 0.86 | SLC6A9 (0.74) | SLC6A9KCNH2 | |
| SCHEMBL3101353 | 0.81 | SLC6A9 (0.58) | SLC6A9KCNH2 | |
| SCHEMBL3107883 | 0.76 | SLC6A9 (0.74) | SLC6A9KCNH2 | |
| SCHEMBL3101590 | 0.75 | SLC6A9 (0.74) | SLC6A9KCNH2 | |
| SCHEMBL7898500 | 0.74 | SLC6A9 (0.82) | SLC6A9KCNH2 | |
| SCHEMBL3089765 | 0.73 | SLC6A9 (0.58) | SLC6A9KCNH2 | |
| SCHEMBL3097604 | 0.72 | SLC6A9 (0.55) | SLC6A9KCNH2 | |
| SCHEMBL3100798 | 0.72 | SLC6A9 (0.55) | SLC6A9 | |
| SCHEMBL7893902 | 0.71 | SLC6A9 (0.71) | SLC6A9KCNH2 | |
| SCHEMBL7895349 | 0.71 | SLC6A9 (0.70) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396296-B1 | AMINOTETRALINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBVIE DEUTSCHLAND (DE) | 2016-05-25 | — | — | EP | claimed |