Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410465 | 0.94 | HDAC1 (0.41) | HDAC1SUCNR1NAMPTGRM2L3MBTL1 | |
| SCHEMBL17764497 | 0.90 | SUCNR1 (0.52) | HDAC1SUCNR1NAMPTNR1H4CFD | |
| SCHEMBL16397314 | 0.90 | SUCNR1 (0.49) | HDAC1SUCNR1NR1H4CFDF11 | |
| SCHEMBL17764279 | 0.85 | SUCNR1 (0.50) | HDAC1SUCNR1CFDF11TPSB2 | |
| SCHEMBL16409648 | 0.84 | HDAC1 (0.47) | HDAC1SUCNR1NAMPTCFDF11 | |
| SCHEMBL16396451 | 0.84 | HDAC1 (0.44) | HDAC1SUCNR1NAMPTHDAC6NR1H4 | |
| SCHEMBL17764426 | 0.82 | MAPT (0.37) | HDAC1SUCNR1L3MBTL1MEN1KMT2A | |
| SCHEMBL17764378 | 0.81 | SUCNR1 (0.51) | HDAC1SUCNR1CFDF11TPSB2 | |
| SCHEMBL16396992 | 0.80 | SUCNR1 (0.60) | HDAC1SUCNR1NR1H4CFDF11 | |
| SCHEMBL16410356 | 0.79 | HDAC1 (0.45) | HDAC1SUCNR1NAMPTCFDF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145247-A1 | Aminomethyl-Biaryl Derivatives Complement Factor D inhibitors and uses thereof | NOVARTIS AG (CH) | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145247-A1 | Aminomethyl-Biaryl Derivatives Complement Factor D inhibitors and uses thereof | CFD, CFH, CFB | HDAC1 3377/4885SUCNR1 4670/4885NAMPT 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.