SCHEMBL177670

SCHEMBL177670

CC(O)C([NH])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2390431 1.00
Hydroxyl Radical SCHEMBL8654033 0.96
SCHEMBL23067 0.78
SCHEMBL7686636 0.73
SCHEMBL1033425 0.72
SCHEMBL43024 0.72
SCHEMBL1086668 0.72
SCHEMBL7728699 0.72
SCHEMBL1086296 0.72
SCHEMBL7012989 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338389-A1 BICYCLIC HETEROCYCLES AS FGFR INHIBITORS INCYTE CORPORATION 2023-10-26 US claimed
CN-116836162-A Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof 南方医科大学 2023-10-03 CN claimed
CN-115835908-A Bicyclic heterocycles as FGFR inhibitors 因赛特公司 2023-03-21 CN claimed
US-11607416-B2 Bicyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2023-03-21 US claimed
EP-4045151-A1 BICYCLIC HETEROCYCLES AS FGFR INHIBITORS Incyte Corporation (US) 2022-08-24 EP claimed
WO-2021076602-A1 BICYCLIC HETEROCYCLES AS FGFR INHIBITORS INCYTE CORPORATION (US) 2021-04-22 WO claimed
US-20210106588-A1 BICYCLIC HETEROCYCLES AS FGFR INHIBITORS INCYTE CORPORATION 2021-04-15 US claimed
US-20180222856-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2018-08-09 US claimed
EP-3328833-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE Vilnius University (LT) 2018-06-06 EP claimed
EP-3127937-B1 FLAME RESISTANT POLYAMIDE 12 SUBSTANCES FOR RAIL APPLICATIONS EMS PATENT AG (CH) 2018-03-07 EP claimed
EP-0310622-B1 ANTI-INFLAMMATORY COMPOSITIONS ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) 1992-04-15 EP claimed
WO-1992002484-A1 PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) 1992-02-20 WO claimed
EP-0455271-A2 Anti-inflammatory compositions PROCYON PHARMACEUTICALS, INC. (US) 1991-11-06 EP claimed
EP-0143001-B1 PYRIMIDOISOQUINOLINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-04-10 EP claimed
US-4920129-A Anti-ulcerative imidazopyridine compounds FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-04-24 US claimed
US-4673676-A Pyrimidoisoquinoline derivatives useful for treating allergies FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-06-16 US claimed
EP-0189687-A1 Soap-based detergent composition containing a bleaching agent UNION GENERALE DE SAVONNERIE Société Anonyme: (FR) 1986-08-06 EP claimed
EP-0143001-A2 Pyrimidoisoquinoline derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-05-29 EP claimed
US-4353834-A Carbonate and carboxylic acid ester group-containing non-ionic surface-active agents BASF WYANDOTTE CORPORATION (US) 1982-10-12 US claimed
US-4243653-A Non-ionic polyiodo sugar substituted anilines THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-01-06 US claimed