SCHEMBL177673

SCHEMBL177673

OB(O)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 4/20 0.52
TSHR P16473 3/20 0.50
TTR P02766 1/20 0.39
CYP3A4 P08684 2/20 0.38
TP53 P04637 1/20 0.38
TPMT P51580 1/20 0.38
ALDH1A1 P00352 2/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ERN1 O75460 1/20 0.35
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
HTR3A P46098 1/20 0.35
HTR3D Q70Z44 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29209517 0.94 ENPP2 (0.52) ENPP2TSHRTTRCYP3A4ALDH1A1
SCHEMBL2144215 0.84 ENPP2 (0.44) ENPP2TSHRTTRCYP3A4ALDH1A1
SCHEMBL2317082 0.82 ENPP2 (0.42) ENPP2TSHRTTRALDH1A1CA2
SCHEMBL31019656 0.82 TSHR (0.42) ENPP2TSHRTTRERN1CA1
SCHEMBL25651924 0.82 CYP3A4 (0.55) ENPP2TSHRTTRCYP3A4TP53
SCHEMBL31590081 0.82 ENPP2 (0.42) ENPP2TSHRTTRERN1CA1
SCHEMBL5524 0.82 ENPP2 (0.42) ENPP2TSHRTTRERN1CA1
SCHEMBL18019531 0.82 TSHR (0.42) ENPP2TSHRTTRERN1CA1
SCHEMBL7085519 0.82 TTR (0.52) ENPP2TTRTP53HSD17B10CA1
SCHEMBL29253984 0.81 TSHR (0.50) ENPP2TSHRTTRCYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2070 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
CN-120118071-A Quinazoline compound and application thereof 北京化工大学 2025-06-10 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119751364-A Dimethoxy quinazoline compound and application thereof 中日友好医院(中日友好临床医学研究所) 2025-04-04 CN claimed
CN-118344321-A Gamma-pyrone derivative and synthetic method and application thereof 武汉轻工大学 2024-07-16 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2004-03-18 US claimed
WO-2004009752-A1 ALKALINE LIQUID DETERGENT COMPOSITION CJ CORPORATION (KR) 2004-01-29 WO claimed
WO-2003105860-A1 PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 2003-12-24 WO claimed
US-20030211138-A1 Temperature control system for cutaneous photodynamic therapy SPECTRA SYSTEMS CORPORATION 2003-11-13 US claimed
WO-2003070315-A2 TEMPERATURE CONTROL SYSTEM FOR CUTANEOUS PHOTODYNAMIC THERAPY SPECTRA SYSTEMS CORPORATION (US) 2003-08-28 WO claimed
US-6590100-B2 Reacting an aromatic compound bearing a leaving group and an arylboronic acid and/or its derivatives in the presence of a base and an effective amount of a nickel catalyst RHODIA CHIMIE (FR) 2003-07-08 US claimed
US-20020173652-A1 Process for preparing a polyaromatic compound SHASUN PHARMA SOLUTIONS, INC. 2002-11-21 US claimed
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO claimed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO claimed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO claimed