Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689749 | 1.00 | MAPK14 (0.34) | MAPK14WNT3AMTORCCNKCDK12 | |
| SCHEMBL17767934 | 1.00 | MAPK14 (0.34) | MAPK14WNT3AMTORCCNKCDK12 | |
| SCHEMBL19689748 | 1.00 | MAPK14 (0.34) | MAPK14WNT3AMTORCCNKCDK12 | |
| SCHEMBL17778758 | 0.92 | KIF18A (0.36) | MAPK14WNT3ACCNKCDK12JAK2 | |
| SCHEMBL17768171 | 0.92 | KIF18A (0.36) | MAPK14WNT3ACCNKCDK12JAK2 | |
| SCHEMBL17768173 | 0.92 | KIF18A (0.36) | MAPK14WNT3ACCNKCDK12JAK2 | |
| SCHEMBL19689739 | 0.91 | HRH3 (0.34) | MAPK14WNT3ACCNKCDK12JAK2 | |
| SCHEMBL17778743 | 0.91 | MAPK14 (0.36) | MAPK14WNT3AMTORCCNKCDK12 | |
| SCHEMBL19706589 | 0.91 | HRH3 (0.34) | MAPK14WNT3ACCNKCDK12JAK2 | |
| SCHEMBL17768114 | 0.91 | MAPK14 (0.36) | MAPK14WNT3AMTORCCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221316-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2017-09-27 | — | — | EP | disclosed |
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |