⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270711 | 0.78 | — | — | |
| SCHEMBL11633803 | 0.76 | — | — | |
| SCHEMBL5586147 | 0.75 | — | — | |
| SCHEMBL269689 | 0.74 | — | — | |
| SCHEMBL12832679 | 0.74 | — | — | |
| SCHEMBL271158 | 0.74 | — | — | |
| SCHEMBL6786995 | 0.74 | — | — | |
| SCHEMBL23044847 | 0.73 | HTR2A (0.37) | — | |
| SCHEMBL178191 | 0.73 | — | — | |
| SCHEMBL29710675 | 0.73 | HTR2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102272093-A | N-(1-hydroxyethyl)carboxamide compound and process for producing same | — | 2011-12-07 | — | — | CN | claimed |
| US-20110294974-A1 | N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | SHOWA DENKO K.K. (JP) | 2011-12-01 | — | — | US | claimed |
| EP-2386538-A1 | N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | Showa Denko K.K. (JP) | 2011-11-16 | — | — | EP | claimed |
| EP-2386538-B1 | N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | SHOWA DENKO KK (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8697912-B2 | N-(1-hydroxyethyl) carboxamide compound and process for producing same | SHOWA DENKO K.K. (JP) | 2014-04-15 | — | — | US | disclosed |
| CN-102272093-A | N-(1-hydroxyethyl)carboxamide compound and process for producing same | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110294974-A1 | N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | SHOWA DENKO K.K. (JP) | 2011-12-01 | — | — | US | disclosed |
| EP-2386538-A1 | N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | Showa Denko K.K. (JP) | 2011-11-16 | — | — | EP | disclosed |