⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733628 | 0.77 | — | — | |
| SCHEMBL177706 | 0.73 | — | — | |
| SCHEMBL787268 | 0.70 | MEN1 (0.32) | — | |
| SCHEMBL170618 | 0.70 | MEN1 (0.32) | — | |
| SCHEMBL16531806 | 0.70 | MEN1 (0.32) | — | |
| SCHEMBL8733636 | 0.70 | — | — | |
| SCHEMBL8997144 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7975590 | 0.69 | MEN1 (0.31) | — | |
| Bromide SCHEMBL11042423 | 0.69 | MEN1 (0.31) | — | |
| SCHEMBL8517090 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386538-B1 | N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | SHOWA DENKO KK (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8697912-B2 | N-(1-hydroxyethyl) carboxamide compound and process for producing same | SHOWA DENKO K.K. (JP) | 2014-04-15 | — | — | US | disclosed |
| CN-102272093-A | N-(1-hydroxyethyl)carboxamide compound and process for producing same | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110294974-A1 | N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | SHOWA DENKO K.K. (JP) | 2011-12-01 | — | — | US | disclosed |
| EP-2386538-A1 | N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME | Showa Denko K.K. (JP) | 2011-11-16 | — | — | EP | disclosed |