Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605247 | 0.84 | TSHR (0.49) | KDM4EGAALIG1KMT2ASMN1; SMN2 | |
| SCHEMBL8321513 | 0.74 | KDM4E (0.41) | KDM4EGAAGLALIG1KMT2A | |
| SCHEMBL6178828 | 0.71 | KDM4E (0.47) | KDM4EGAAGLAKMT2ASMN1; SMN2 | |
| SCHEMBL30195826 | 0.70 | LIG1 (0.68) | KDM4EGAALIG1KMT2ASMN1; SMN2 | |
| SCHEMBL385145 | 0.70 | LIG1 (0.68) | KDM4EGAALIG1KMT2ASMN1; SMN2 | |
| SCHEMBL70624 | 0.70 | GAA (0.67) | KDM4EGAAGLAKMT2AALDH1A1 | |
| SCHEMBL1842460 | 0.70 | KDM4E (0.68) | KDM4EGAAGLAKMT2AALDH1A1 | |
| SCHEMBL17770655 | 0.70 | KDM4E (0.68) | KDM4EGAAGLAKMT2ASMN1; SMN2 | |
| SCHEMBL10464803 | 0.70 | KDM4E (1.00) | KDM4EGAAGLAKMT2ASMN1; SMN2 | |
| SCHEMBL11603141 | 0.70 | AKR1C3 (0.37) | KDM4EGAAGLASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079502-A1 | METAL CHELATING COMPOUNDS FOR USE IN TREATING DISEASES | UNIVERSITY OF NORTHUMBRIA (GB) | 2016-05-26 | — | — | WO | disclosed |