Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17770659 | 0.84 | KDM4E (0.53) | TSHRGAALIG1KDM4EMAPT | |
| SCHEMBL11603141 | 0.82 | AKR1C3 (0.37) | TSHRGAAKDM4EHPGDALDH1A1 | |
| SCHEMBL11604724 | 0.76 | XDH (0.42) | KDM4ECA9HPGDMAPTALDH1A1 | |
| SCHEMBL11532625 | 0.75 | SRD5A2 (0.55) | KDM4EHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL11607350 | 0.75 | CNR2 (0.47) | TSHRCA9HPGDALDH1A1TP53 | |
| SCHEMBL11591989 | 0.74 | ALDH1A1 (0.47) | TSHRHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL14332793 | 0.73 | KDM4E (0.53) | TSHRGAAKDM4ECA12CA1 | |
| SCHEMBL11532467 | 0.72 | RHEB (0.55) | KDM4EHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL11538794 | 0.72 | RXRA (0.49) | CA12CA9HPGDALDH1A1KMT2A | |
| SCHEMBL11603123 | 0.71 | KDM4E (0.35) | TSHRGAAKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083850-A | HYPOTENSIVE AGENTS | MEIJI SEIKA KAISHA LTD. (JA) | 1978-04-11 | — | — | US | disclosed |