Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.58 |
| ▸ | MME | P08473 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12527668 | 0.92 | ACE (0.50) | ACEMMEAPP | |
| SCHEMBL12495263 | 0.83 | ACE (0.43) | ACEMMEAPP | |
| SCHEMBL12528397 | 0.81 | ACE (0.62) | ACEMMEAPP | |
| SCHEMBL12527932 | 0.80 | ACE (0.67) | ACEMMEAPP | |
| SCHEMBL12527936 | 0.80 | ACE (0.67) | ACEMMEAPP | |
| SCHEMBL17771375 | 0.79 | ACE (0.61) | ACEMMEAPP | |
| SCHEMBL12528375 | 0.78 | ACE (0.64) | ACEMMEAPP | |
| SCHEMBL12525728 | 0.78 | ACE (0.59) | ACEMMEAPP | |
| SCHEMBL17771398 | 0.78 | ACE (0.55) | ACEMMEAPP | |
| SCHEMBL17771414 | 0.78 | ACE (0.63) | ACEMMEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |