Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17772142 | 0.84 | CYP4F2 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL17772118 | 0.81 | ACACB (0.35) | ACACBACACACYP4F2CYP4A11 | |
| SCHEMBL31108901 | 0.77 | ACACB (0.48) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL798475 | 0.74 | CYP4F2 (0.50) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL186855 | 0.73 | ACACB (0.66) | ACACBACACAACLY | |
| SCHEMBL2737164 | 0.72 | ACACB (0.51) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL186569 | 0.72 | ACACB (0.69) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL773091 | 0.72 | ACLY (0.50) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL1151614 | 0.71 | ACACB (0.46) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL13818712 | 0.71 | ACACB (0.67) | ACACBACACAACLYCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402300-B1 | Hydroxyl compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS INC (US) | 2016-05-25 | — | — | EP | disclosed |