Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 16/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106034 | 0.85 | SLC6A9 (0.63) | SLC6A9KCNH2 | |
| SCHEMBL3097290 | 0.81 | SLC6A9 (0.59) | SLC6A9KCNH2 | |
| SCHEMBL3108597 | 0.79 | SLC6A9 (0.65) | SLC6A9KCNH2 | |
| SCHEMBL3106030 | 0.79 | SLC6A9 (0.40) | SLC6A9KCNH2NQO2MTNR1AMTNR1B | |
| SCHEMBL3099198 | 0.79 | SLC6A9 (0.65) | SLC6A9KCNH2NPY5R | |
| SCHEMBL3103959 | 0.79 | SLC6A9 (0.52) | SLC6A9KCNH2 | |
| SCHEMBL3109073 | 0.77 | SLC6A9 (0.68) | SLC6A9KCNH2 | |
| SCHEMBL3098525 | 0.76 | SLC6A9 (0.77) | SLC6A9KCNH2NPY5R | |
| SCHEMBL3097299 | 0.75 | SLC6A9 (0.46) | SLC6A9NQO2MTNR1AMTNR1B | |
| SCHEMBL17772428 | 0.74 | SLC6A9 (0.46) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396296-B1 | AMINOTETRALINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBVIE DEUTSCHLAND (DE) | 2016-05-25 | — | — | EP | disclosed |