Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | PPM1B | O75688 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | GMNN | O75496 | 3/20 | 1.00 |
| ▸ | TFPI2 | P48307 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 3/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 3/20 | 1.00 |
| ▸ | THPO | P40225 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | PPP1CC | P36873 | 2/20 | 1.00 |
| ▸ | PPP5C | P53041 | 2/20 | 1.00 |
| ▸ | PPP1CA | P62136 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norcantharidin SCHEMBL29380910 | 1.00 | TP53 (1.00) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL9675442 | 1.00 | TP53 (1.00) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL3187662 | 1.00 | TP53 (1.00) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL3195020 | 1.00 | TP53 (1.00) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL19318920 | 1.00 | TP53 (1.00) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL6432892 | 1.00 | TP53 (1.00) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL9906842 | 1.00 | TP53 (1.00) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| SCHEMBL16938608 | 0.84 | KDM4E (0.71) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| SCHEMBL17695028 | 0.84 | KDM4E (0.71) | TP53LMNAPPM1BSMN1; SMN2KDM4E | |
| SCHEMBL12599313 | 0.74 | KDM4E (0.57) | TP53LMNAPPM1BSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2318 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302794-A1 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE TREATMENT OF CUTANEOUS DISORDERS | VERRICA PHARMACEUTICALS INC. (US) | 2025-10-02 | — | — | US | claimed |
| CN-119899198-A | Norcantharidin derivative and preparation method and application thereof | 中国科学技术大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119499210-A | Doxorubicin-tetravalent platinum drug-norcantharidin three-drug combination nano-drug, and preparation method and application thereof | 齐鲁工业大学(山东省科学院) | 2025-02-25 | — | — | CN | claimed |
| CN-119258021-A | Norcantharidin liposome injection and preparation method and application thereof | 沈阳药科大学 | 2025-01-07 | — | — | CN | claimed |
| CN-119236093-A | Precursor nano self-assembled immune composition and preparation method and application thereof | 南开大学 | 2025-01-03 | — | — | CN | claimed |
| CN-119174727-A | Preparation of copper ion-mediated glycyrrhizic acid and norcantharidin ternary carrier-free co-assembled injectable hydrogel and anti-tumor application thereof | 北京中医药大学 | 2024-12-24 | — | — | CN | claimed |
| CN-119112783-A | PH-sensitive norcantharidin solid self-microemulsion and preparation method and application thereof | 安徽中医药大学 | 2024-12-13 | — | — | CN | claimed |
| US-20240374571-A1 | PHARMACEUTICAL COMBINATIONS COMPRISING A TEAD INHIBITOR AND USES THEREOF FOR THE TREATMENT OF CANCERS | NOVARTIS AG (CH) | 2024-11-14 | — | — | US | claimed |
| CN-118662498-A | Antitumor composition and application thereof | 遵义医科大学 | 2024-09-20 | — | — | CN | claimed |
| CN-118515683-A | Broad-spectrum anticancer drug MCPC2 and preparation method and application thereof | 上海市公共卫生临床中心 | 2024-08-20 | — | — | CN | claimed |
| CN-1557487-A | Immunogenicity composition for preventing and treating diseases and its preparation | 郭占军 | 2004-12-29 | — | — | CN | claimed |
| CN-1557298-A | Injectio Natarii Norcantharidatis freeze-drying powder injection and its preparation method | 肖广常 | 2004-12-29 | — | — | CN | claimed |
| CN-1557299-A | Injectio Natarii Norcantharidatis infusion and its preparation method | 肖广常 | 2004-12-29 | — | — | CN | claimed |
| CN-1520823-A | Novel compound antineoplastic drug preparing process | 沈 恒 | 2004-08-18 | — | — | CN | claimed |
| CN-1493279-A | Norcantharidin drip pill and its preparation method | 南昌弘益科技有限公司 | 2004-05-05 | — | — | CN | claimed |
| CN-1478550-A | Egg yolk antibody composition for preventing and treating atypical pneumonia and its preparation method | 郭占军 | 2004-03-03 | — | — | CN | claimed |
| CN-1460522-A | Egg yolk antibody composite for preventing and curing diseases and its preparaion method | GUO ZHANJUN (CN) | 2003-12-10 | — | — | CN | claimed |
| CN-1418622-A | Demethyl catharidine lipid for treating malignant tumour, and its prepn. method | WANG DENGZHI (CN) | 2003-05-21 | — | — | CN | claimed |
| CN-1385154-A | Slow-releasing injection type demehylcantharidin for antitumor | NO 2 MILITARY MEDICAL UNIV OF (CN) | 2002-12-18 | — | — | CN | claimed |
| CN-1087526-A | A Gan goes anticancer preparation prescription and technology | UNIV BEIJING MEDICAL (CN) | 1994-06-08 | — | — | CN | claimed |