Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 20/20 | 1.00 |
| ▸ | FDPS | P14324 | 2/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29604112 | 1.00 | GGPS1 (1.00) | GGPS1FDPS | |
| SCHEMBL29525919 | 0.93 | GGPS1 (1.00) | GGPS1FDPS | |
| SCHEMBL12257803 | 0.85 | GGPS1 (0.74) | GGPS1FDPS | |
| SCHEMBL12060535 | 0.83 | GGPS1 (0.72) | GGPS1FDPS | |
| SCHEMBL12257805 | 0.82 | GGPS1 (0.88) | GGPS1FDPS | |
| SCHEMBL12257820 | 0.80 | GGPS1 (0.88) | GGPS1FDPS | |
| SCHEMBL12060529 | 0.80 | GGPS1 (0.86) | GGPS1FDPS | |
| SCHEMBL12060539 | 0.80 | GGPS1 (0.86) | GGPS1FDPS | |
| SCHEMBL12257807 | 0.80 | GGPS1 (0.86) | GGPS1FDPS | |
| SCHEMBL12257838 | 0.80 | GGPS1 (0.66) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016081281-A1 | LIPOPHILIC BISPHOSPHONATES AND METHODS OF USE | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2016-05-26 | — | — | WO | disclosed |