Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 20/20 | 1.00 |
| ▸ | FDPS | P14324 | 2/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17777274 | 1.00 | GGPS1 (1.00) | GGPS1FDPS | |
| SCHEMBL29525919 | 0.93 | GGPS1 (1.00) | GGPS1FDPS | |
| SCHEMBL12257803 | 0.85 | GGPS1 (0.74) | GGPS1FDPS | |
| SCHEMBL12060535 | 0.83 | GGPS1 (0.72) | GGPS1FDPS | |
| SCHEMBL12257805 | 0.82 | GGPS1 (0.88) | GGPS1FDPS | |
| SCHEMBL12257820 | 0.80 | GGPS1 (0.88) | GGPS1FDPS | |
| SCHEMBL12060529 | 0.80 | GGPS1 (0.86) | GGPS1FDPS | |
| SCHEMBL12060539 | 0.80 | GGPS1 (0.86) | GGPS1FDPS | |
| SCHEMBL12257807 | 0.80 | GGPS1 (0.86) | GGPS1FDPS | |
| SCHEMBL12257838 | 0.80 | GGPS1 (0.66) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367283-A1 | MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT | TSINGHUA UNIVERSITY (CN) | 2025-12-04 | — | — | US | disclosed |
| CN-119097698-A | Inhibitors of mevalonate pathway as efficient vaccine adjuvants | 清华大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-114848656-B | Inhibitors of mevalonate pathway as efficient vaccine adjuvants | 清华大学 | 2024-09-27 | — | — | CN | disclosed |
| US-20220387584-A1 | MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT | TSINGHUA UNIVERSITY (CN) | 2022-12-08 | — | — | US | disclosed |
| CN-114848656-A | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-08-05 | — | — | CN | disclosed |
| US-11382971-B2 | Mevalonate pathway inhibitor as highly-efficient vaccine adjuvant | TSINGHUA UNIVERSITY (CN) | 2022-07-12 | — | — | US | disclosed |
| CN-108289902-B | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-05-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367283-A1 | MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT | COASY, GGPS1, HMGCR | GGPS1 2/4885FDPS 4/4885 |
| US-11382971-B2 | Mevalonate pathway inhibitor as highly-efficient vaccine adjuvant | GGPS1, HMGCR, COASY | GGPS1 1/4885FDPS 4/4885 |
| US-20220387584-A1 | MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT | COASY, GGPS1, HMGCR | GGPS1 2/4885FDPS 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.