Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754528 | 0.94 | CA2 (0.36) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL16754530 | 0.94 | CA2 (0.36) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL16754531 | 0.94 | CA2 (0.36) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL19689750 | 0.93 | CA2 (0.38) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL19706916 | 0.92 | CA2 (0.37) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL19689682 | 0.92 | CA2 (0.37) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL17778435 | 0.90 | KDM4E (0.33) | CA2CA9LIPGLPLLIPC | |
| SCHEMBL19699685 | 0.90 | CA2 (0.37) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL17768179 | 0.89 | CA2 (0.36) | CA2CA9KMOKDM1AMAOA | |
| SCHEMBL19706656 | 0.89 | CA2 (0.36) | CA2CA9KMOKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |