Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754694 | 1.00 | MAP4K4 (0.32) | MAP4K4MEN1KMT2A | |
| SCHEMBL16754611 | 1.00 | MAP4K4 (0.32) | MAP4K4MEN1KMT2A | |
| SCHEMBL16754610 | 1.00 | MAP4K4 (0.32) | MAP4K4MEN1KMT2A | |
| SCHEMBL16237499 | 0.82 | MAP4K4 (0.49) | MAP4K4 | |
| SCHEMBL20632886 | 0.82 | MAP4K4 (0.49) | MAP4K4 | |
| SCHEMBL16249992 | 0.82 | MAP4K4 (0.49) | MAP4K4 | |
| SCHEMBL17778379 | 0.82 | MAP4K4 (0.49) | MAP4K4 | |
| SCHEMBL19699035 | 0.81 | MAP4K4 (0.48) | MAP4K4 | |
| SCHEMBL16754566 | 0.81 | MAP4K4 (0.46) | MAP4K4 | |
| SCHEMBL17778528 | 0.81 | MAP4K4 (0.46) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079711-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |