Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | POLQ | O75417 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775470 | 0.81 | POLQ (0.47) | DRD4POLQPOLB | |
| SCHEMBL6986705 | 0.78 | ALDH1A1 (0.45) | F2ACE | |
| SCHEMBL17775469 | 0.77 | F10 (0.47) | F2ACE | |
| SCHEMBL197944 | 0.75 | ACE (0.55) | F2MAPTACE | |
| SCHEMBL5639706 | 0.75 | ACE (0.55) | F2MAPTACE | |
| SCHEMBL1527368 | 0.75 | ACE (0.55) | F2MAPTACE | |
| SCHEMBL7340784 | 0.74 | ACE (0.54) | F2MAPTACE | |
| Hydrochloric Acid SCHEMBL10792376 | 0.74 | ACE (0.54) | F2MAPTACE | |
| Hydrochloric Acid SCHEMBL10792372 | 0.74 | ACE (0.54) | F2MAPTACE | |
| SCHEMBL10893075 | 0.74 | ACE (0.54) | F2MAPTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765099-B2 | STAT6 inhibitors | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160145279-A1 | STAT6 INHIBITORS | BAYLOR COLLEGE OF MEDICINE (US) | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145279-A1 | STAT6 INHIBITORS | STAT6, STAT3, STAT1 | DRD4 4609/4885POLQ 4139/4885POLB 4569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.