Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779813 | 0.94 | MCL1 (0.43) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL17682948 | 0.94 | MCL1 (0.43) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL17683012 | 0.88 | ESR2 (0.45) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL17682966 | 0.86 | HSD17B1 (0.45) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL17779750 | 0.85 | HSD17B1 (0.43) | HSD17B1HSD17B2MCL1HDAC8ESR1 | |
| SCHEMBL17683009 | 0.85 | HSD17B1 (0.46) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL17682964 | 0.83 | MCL1 (0.43) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL17779814 | 0.83 | HSD17B1 (0.47) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL25494821 | 0.81 | MCL1 (0.49) | CA12CA1CA2CA9HSD17B1 | |
| SCHEMBL17683003 | 0.81 | MCL1 (0.45) | CA12CA1CA2CA9HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160149139-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-05-26 | — | — | US | disclosed |