Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311212 | 1.00 | MAOB (0.42) | MAOBMAOAMEN1KMT2AFAAH | |
| SCHEMBL1959242 | 0.87 | KDM4E (0.46) | MAOBMAOAMEN1KMT2AMMP13 | |
| SCHEMBL19060472 | 0.83 | MAPK1 (0.35) | MAOBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4724622 | 0.81 | MAPT (0.38) | MAOBMEN1KMT2ACCNB2CDK1 | |
| SCHEMBL10123179 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3097423 | 0.76 | GLA (0.52) | MAOBMAOAMEN1KMT2AFAAH | |
| SCHEMBL1486473 | 0.74 | FFAR1 (0.46) | MAOBMEN1KMT2AFAAHMGLL | |
| SCHEMBL12003807 | 0.71 | ALDH1A1 (0.67) | MAOBMAOAMEN1KMT2ANR4A2 | |
| SCHEMBL2496071 | 0.71 | MAOB (0.42) | MAOBMAOAFAAHMGLLNR4A2 | |
| SCHEMBL23838435 | 0.69 | MAOB (0.57) | MAOBMAOANR4A2GRM5CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392110-A1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2020-12-17 | — | — | US | disclosed |
| EP-3415501-B9 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2020-12-02 | — | — | EP | disclosed |
| US-10676462-B2 | Quinoline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2020-06-09 | — | — | US | disclosed |
| EP-3415501-B1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2020-04-08 | — | — | EP | disclosed |
| US-10501442-B2 | Quinoline derivative | ONO PHARMACEUTICALS CO., LTD. (JP) | 2019-12-10 | — | — | US | disclosed |
| US-20190135785-A1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2019-05-09 | — | — | US | disclosed |
| US-10208022-B2 | Quinoline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2019-02-19 | — | — | US | disclosed |
| EP-3415501-A1 | QUINOLINE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2018-12-19 | — | — | EP | disclosed |
| US-20180258072-A1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-09-13 | — | — | US | disclosed |
| US-9994549-B2 | Quinoline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-06-12 | — | — | US | disclosed |
| US-20170088542-A1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-03-30 | — | — | US | disclosed |
| US-9573935-B2 | Quinoline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160168121-A1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-06-16 | — | — | US | disclosed |
| EP-3026045-A1 | QUINOLINE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2016-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392110-A1 | QUINOLINE DERIVATIVE | FLT3, AXL, ERBB2 | MAOB 1728/4885MAOA 2085/4885MEN1 1237/4885 |
| US-10501442-B2 | Quinoline derivative | FLT3, AXL, ERBB2 | MAOB 1728/4885MAOA 2085/4885MEN1 1237/4885 |
| US-20180258072-A1 | QUINOLINE DERIVATIVE | FLT3, AXL, ERBB2 | MAOB 1728/4885MAOA 2085/4885MEN1 1237/4885 |
| US-10208022-B2 | Quinoline derivative | FLT3, AXL, ERBB2 | MAOB 1728/4885MAOA 2085/4885MEN1 1237/4885 |
| US-20160168121-A1 | QUINOLINE DERIVATIVE | FLT3, AXL, ERBB2 | MAOB 1637/4885MAOA 2142/4885MEN1 790/4885 |
| US-20170088542-A1 | QUINOLINE DERIVATIVE | FLT3, AXL, ERBB2 | MAOB 1728/4885MAOA 2085/4885MEN1 1237/4885 |
| US-10676462-B2 | Quinoline derivative | FLT3, AXL, ERBB2 | MAOB 1728/4885MAOA 2085/4885MEN1 1237/4885 |
| US-20190135785-A1 | QUINOLINE DERIVATIVE | FLT3, AXL, ERBB2 | MAOB 1728/4885MAOA 2085/4885MEN1 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.