Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 8/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17781893 | 0.95 | AGTR2 (0.56) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL17781901 | 0.93 | AGTR2 (0.58) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL17781895 | 0.87 | AGTR2 (0.60) | AGTR2CYP2C9CYP2B6AGTR1 | |
| SCHEMBL4187910 | 0.85 | AGTR2 (0.69) | AGTR2CYP2C9CYP2B6AGTR1 | |
| SCHEMBL4183324 | 0.85 | AGTR2 (0.65) | AGTR2CYP2C9CYP2B6AGTR1 | |
| SCHEMBL4188608 | 0.82 | AGTR2 (0.66) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4183014 | 0.81 | AGTR2 (0.64) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL17781906 | 0.80 | AGTR2 (0.68) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4183361 | 0.80 | AGTR2 (0.68) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4194934 | 0.80 | AGTR2 (0.62) | AGTR2CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869009-B1 | NEW BICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2016-06-01 | — | — | EP | claimed |