Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 8/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188604 | 0.89 | AGTR2 (0.63) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4183350 | 0.85 | AGTR2 (0.66) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4183359 | 0.85 | AGTR2 (0.68) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4192597 | 0.84 | AGTR2 (0.64) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4187909 | 0.84 | AGTR2 (0.66) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL17781912 | 0.83 | AGTR2 (0.63) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL17781909 | 0.83 | AGTR2 (0.63) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL17781904 | 0.82 | AGTR2 (0.68) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4187904 | 0.82 | AGTR2 (0.68) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4195042 | 0.81 | AGTR2 (0.61) | AGTR2CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869009-B1 | NEW BICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2016-06-01 | — | — | EP | claimed |