SCHEMBL1778452

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1778583	0.94	PTGDR2 (0.44)	PTGDR2L3MBTL1ENPP3CCNE1CDK2
	SCHEMBL3111731	0.91	SCN9A (0.42)	PTGDR2L3MBTL1SCN9AENPP3CCNE1
	SCHEMBL1779187	0.86	L3MBTL1 (0.48)	PTGDR2L3MBTL1ENPP3CCNE1CDK2
	SCHEMBL1778089	0.86	L3MBTL1 (0.43)	PTGDR2L3MBTL1SCN9AENPP3CCNE1
	SCHEMBL3103172	0.84	PTGDR2 (0.42)	PTGDR2L3MBTL1ENPP3CCNE1CDK2
	SCHEMBL1777336	0.83	L3MBTL1 (0.46)	PTGDR2L3MBTL1ENPP3CCNE1CDK2
	SCHEMBL1780127	0.83	PTGDR2 (0.43)	PTGDR2L3MBTL1ENPP3CCNE1CDK2
	SCHEMBL1778785	0.83	IGF1R (0.50)	PTGDR2L3MBTL1ENPP3CCNE1CDK2
	SCHEMBL6140206	0.82	L3MBTL1 (0.47)	PTGDR2L3MBTL1ENPP3CCNE1CDK2
	SCHEMBL1780028	0.82	PTGDR2 (0.43)	PTGDR2L3MBTL1ENPP3CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.