Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.31 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.31 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778552 | 1.00 | ITGAL (0.66) | ITGALGAACPB1CTSLCTSB | |
| SCHEMBL4638237 | 1.00 | ITGAL (0.66) | ITGALGAACPB1CTSLCTSB | |
| SCHEMBL4639099 | 0.95 | ITGAL (0.67) | ITGALGAACTSLCTSBCTSS | |
| SCHEMBL1777096 | 0.95 | ITGAL (0.67) | ITGALGAACTSLCTSBCTSS | |
| SCHEMBL1777099 | 0.95 | ITGAL (0.67) | ITGALGAACTSLCTSBCTSS | |
| SCHEMBL1777060 | 0.94 | ITGAL (0.64) | ITGALGAACTSLCTSBCTSS | |
| SCHEMBL1777058 | 0.94 | ITGAL (0.64) | ITGALGAACTSLCTSBCTSS | |
| SCHEMBL4637570 | 0.94 | ITGAL (0.64) | ITGALGAACTSLCTSBCTSS | |
| SCHEMBL1777467 | 0.94 | ITGAL (0.63) | ITGALGAACTSLHTT | |
| SCHEMBL4638326 | 0.94 | ITGAL (0.63) | ITGALGAACTSLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943660-B2 | 2-(carboxyalkylaminocarbonyl)-pyrrolidines as antiinflammatory, immunosupressant, or antimetastasis agents | DOMINION PHARMAKINE S.L. (ES) | 2011-05-17 | — | — | US | disclosed |
| US-20080249157-A1 | Novel Inhibitors of the Lfa-1/Icam-1 Interaction and Uses Thereof | DOMINION PHARMAKINE S.L. (ES) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249157-A1 | Novel Inhibitors of the Lfa-1/Icam-1 Interaction and Uses Thereof | ICAM1, VCAM1, SELL | ITGAL 12/4885GAA 627/4885CPB1 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.