Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | CSNK2A2 | P19784 | 10/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 10/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786403 | 0.87 | CSNK2A2 (0.73) | FYNABCB1MEN1KMT2AKDM4E | |
| SCHEMBL15265120 | 0.84 | CSNK2A2 (0.80) | FYNABCB1MEN1KMT2AKDM4E | |
| SCHEMBL16894645 | 0.84 | ABCB1 (0.68) | FYNABCB1MEN1KMT2AKDM4E | |
| SCHEMBL18613228 | 0.84 | FYN (1.00) | FYNABCB1MEN1KMT2AKDM4E | |
| SCHEMBL30521708 | 0.84 | FYN (1.00) | FYNABCB1MEN1KMT2AKDM4E | |
| SCHEMBL27908290 | 0.84 | CSNK2A2 (0.80) | FYNABCB1MEN1KMT2AKDM4E | |
| SCHEMBL925773 | 0.84 | MAPT (0.79) | ABCB1MEN1KMT2AKDM4ECYP3A4 | |
| 3',4'-Dimethoxyflavone SCHEMBL29623082 | 0.82 | CYP3A4 (1.00) | FYNABCB1MEN1KMT2AKDM4E | |
| 3',4'-Dimethoxyflavone SCHEMBL1675954 | 0.82 | CYP3A4 (1.00) | FYNABCB1MEN1KMT2AKDM4E | |
| SCHEMBL17786334 | 0.81 | EGFR (0.67) | ABCB1MEN1KMT2AKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016083490-A1 | COMPOUNDS FOR THE TREATMENT OF AMYLOID-ASSOCIATED DISEASES | REMYND NV (BE) | 2016-06-02 | — | — | WO | disclosed |