Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786507 | 0.84 | STS (0.45) | STSAPPALDH1A1HPGDMAPT | |
| SCHEMBL1374464 | 0.81 | ALDH1A1 (0.69) | STSAPPALDH1A1HPGDMAPT | |
| SCHEMBL17786521 | 0.81 | ALDH1A1 (0.68) | STSAPPALDH1A1HPGDMAPT | |
| SCHEMBL2305474 | 0.81 | STS (0.57) | STSALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10714283 | 0.75 | STS (0.55) | STSAPPALDH1A1HPGDMAPT | |
| SCHEMBL13299937 | 0.74 | ESR1 (0.50) | STSAPPALDH1A1HPGDMAPT | |
| SCHEMBL17786496 | 0.73 | NQO2 (0.57) | STSALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11477316 | 0.73 | STS (0.49) | STSALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL15089105 | 0.73 | ALDH1A1 (0.52) | APPALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11476689 | 0.73 | ALDH1A1 (0.59) | STSALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016083490-A1 | COMPOUNDS FOR THE TREATMENT OF AMYLOID-ASSOCIATED DISEASES | REMYND NV (BE) | 2016-06-02 | — | — | WO | disclosed |