Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 14/20 | 0.37 |
| ▸ | F11 | P03951 | 6/20 | 0.36 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786819 | 0.75 | KLKB1 (0.56) | KLKB1F11F2 | |
| SCHEMBL31352698 | 0.72 | KLKB1 (0.44) | KLKB1 | |
| SCHEMBL17787030 | 0.72 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL17786970 | 0.70 | KLKB1 (0.59) | KLKB1F11F2 | |
| SCHEMBL24344259 | 0.70 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL17786925 | 0.69 | KLKB1 (0.57) | KLKB1F11F2 | |
| SCHEMBL370508 | 0.69 | KMT2A (0.53) | KLKB1 | |
| SCHEMBL16246727 | 0.68 | KLKB1 (0.59) | KLKB1F11 | |
| SCHEMBL17786902 | 0.67 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL17786993 | 0.67 | KLKB1 (0.52) | KLKB1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016083816-A1 | N-((HETEROARYLMETHYL)-HETEROARYL-CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2016-06-02 | — | — | WO | disclosed |