Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037160 | 0.83 | MEN1 (0.49) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL15083132 | 0.82 | TDP1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL1082707 | 0.82 | TDP1 (0.56) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL17520228 | 0.81 | MEN1 (0.51) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL1785039 | 0.81 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL15295921 | 0.81 | TDP1 (0.43) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL19337998 | 0.81 | TDP1 (0.43) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL17793915 | 0.80 | TDP1 (0.40) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL10037156 | 0.77 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL22188082 | 0.77 | MEN1 (0.40) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016086136-A1 | FATTY ACID CYSTEAMINE CONJUGATES OF CFTR MODULATORS AND THEIR USE IN TREATING MEDICAL DISORDERS | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |
| WO-2016086136-A1 | FATTY ACID CYSTEAMINE CONJUGATES OF CFTR MODULATORS AND THEIR USE IN TREATING MEDICAL DISORDERS | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |