SCHEMBL1785039

SCHEMBL1785039

CC(C)(C)OC(=O)NCCSSCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
TSHR P16473 2/20 0.45
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
IDO1 P14902 2/20 0.42
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA12 O43570 3/20 0.41
CA9 Q16790 3/20 0.41
EPHX1 P07099 1/20 0.41
HTT P42858 1/20 0.40
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 1/20 0.37
GFER P55789 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10037156 0.92 MEN1 (0.50) MEN1KMT2AGAATDP1TSHR
SCHEMBL1082707 0.91 TDP1 (0.56) MEN1KMT2AGAATDP1TSHR
SCHEMBL25461951 0.91 MEN1 (0.45) MEN1KMT2AGAATDP1TSHR
SCHEMBL23034976 0.91 MEN1 (0.45) MEN1KMT2AGAATDP1MAOA
SCHEMBL10037160 0.88 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL6478259 0.88 KMT2A (0.49) MEN1KMT2AGAATDP1TSHR
SCHEMBL10037287 0.87 TDP1 (0.46) MEN1KMT2AGAATDP1TSHR
SCHEMBL25014915 0.84 TDP1 (0.50) MEN1KMT2AGAATDP1TSHR
SCHEMBL14646688 0.84 TDP1 (0.50) MEN1KMT2AGAATDP1TSHR
SCHEMBL1042383 0.84 TDP1 (0.59) MEN1KMT2AGAATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4466248-A1 LIPIDIC COMPOUNDS, AND USES THEREOF Sanofi (FR) 2024-11-27 EP disclosed
CN-118829624-A Lipid compound and use thereof 赛诺菲 2024-10-22 CN disclosed
CN-118591560-A Combination therapy for cancer 葛兰素史密斯克莱知识产权发展有限公司 2024-09-03 CN disclosed
US-20230375537-A1 BASE MATERIAL FOR MANUFACTURING SENSOR FOR ANALYZING DETECTION OBJECT, SENSOR FOR ANALYZING DETECTION OBJECT, AND METHOD FOR ANALYZING DETECTION OBJECT NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2023-11-23 US disclosed
US-20230375537-A1 BASE MATERIAL FOR MANUFACTURING SENSOR FOR ANALYZING DETECTION OBJECT, SENSOR FOR ANALYZING DETECTION OBJECT, AND METHOD FOR ANALYZING DETECTION OBJECT NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2023-11-23 US disclosed
WO-2023135305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF SANOFI (FR) 2023-07-20 WO disclosed
US-20230152306-A1 NANOPARTICLES FOR SENSING USE AND PRODUCTION METHOD FOR SAME TearExo Inc. (JP) 2023-05-18 US disclosed
US-20230152306-A1 NANOPARTICLES FOR SENSING USE AND PRODUCTION METHOD FOR SAME TearExo Inc. (JP) 2023-05-18 US disclosed
US-10107798-B2 Methods of chemotype evolution SUNESIS PHARMACEUTICALS, INC. (US) 2018-10-23 US disclosed
US-20180238863-A1 CHEMICAL SYNTHESIS SUNESIS PHARMACEUTICALS, INC. (US) 2018-08-23 US disclosed
US-20110263514-A1 DELIVERY OF AGENTS USING INTERFERING NANOPARTICLES SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2011-10-27 US disclosed
WO-2011116152-A2 DELIVERY OF AGENTS USING INTERFERING NANOPARTICLES SANFORD -BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2011-09-22 WO disclosed
US-20110118126-A1 METHODS OF CHEMOTYPE EVOLUTION SUNESIS PHARMACEUTICALS, INC. 2011-05-19 US disclosed
US-20110118126-A1 METHODS OF CHEMOTYPE EVOLUTION SUNESIS PHARMACEUTICALS, INC. 2011-05-19 US disclosed
US-20110118126-A1 METHODS OF CHEMOTYPE EVOLUTION SUNESIS PHARMACEUTICALS, INC. 2011-05-19 US disclosed
EP-2257637-A1 METHODS OF CHEMOTYPE EVOLUTION Sunesis Pharmaceuticals, Inc. (US) 2010-12-08 EP disclosed
WO-2009120795-A1 METHODS OF CHEMOTYPE EVOLUTION SUNESIS PHARMACEUTICALS, INC. (US) 2009-10-01 WO disclosed
WO-2009120795-A1 METHODS OF CHEMOTYPE EVOLUTION SUNESIS PHARMACEUTICALS, INC. (US) 2009-10-01 WO disclosed
US-20080261831-A1 Ligands and libraries of ligands WELLS JIM 2008-10-23 US disclosed
US-20080261831-A1 Ligands and libraries of ligands WELLS JIM 2008-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263514-A1 DELIVERY OF AGENTS USING INTERFERING NANOPARTICLES SNRPE, SNRPF, SNRPA MEN1 2561/4885KMT2A 3072/4885GAA 1918/4885
US-20180238863-A1 CHEMICAL SYNTHESIS COASY, FASN, DHPS MEN1 1215/4885KMT2A 1758/4885GAA 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.