Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161061 | 0.93 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL20365011 | 0.89 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12624014 | 0.82 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12622049 | 0.82 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12624004 | 0.80 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12623983 | 0.80 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL20787973 | 0.79 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12627182 | 0.79 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL15693684 | 0.79 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL15693682 | 0.78 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222368-B2 | Alzheimer's disease assay in a living patient | PAIN THERAPEUTICS, INC. (US) | 2019-03-05 | — | — | US | disclosed |
| US-9500640-B2 | Alzheimer's disease assay in a living patient | PAIN THERAPEUTICS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-9500640-B2 | Alzheimer's disease assay in a living patient | PAIN THERAPEUTICS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-9354223-B2 | Alzheimer's disease assay in a living patient | PAIN THERAPEUTICS INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-9354223-B2 | Alzheimer's disease assay in a living patient | PAIN THERAPEUTICS INC. (US) | 2016-05-31 | — | — | US | disclosed |