SCHEMBL177890

SCHEMBL177890

C=Cc1ccccc1/N=N/c1ccccc1C=C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
NPC1 O15118 2/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 2/20 0.38
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28827287 0.89 ALDH1A1 (0.50) ALDH1A1NPC1MEN1LMNAKMT2A
SCHEMBL3312608 0.89 ALDH1A1 (0.50) ALDH1A1NPC1MEN1LMNAKMT2A
SCHEMBL15966242 0.86 ALDH1A1 (0.41) ALDH1A1NPC1MEN1LMNAKMT2A
SCHEMBL14314946 0.82 ALDH1A1 (0.46) ALDH1A1MEN1LMNAKMT2ATSHR
SCHEMBL10416209 0.81 ALDH1A1 (0.38) ALDH1A1
SCHEMBL10416207 0.81 ALDH1A1 (0.38) ALDH1A1
SCHEMBL942936 0.80 ALDH1A1 (0.44) ALDH1A1MEN1LMNAKMT2AL3MBTL1
SCHEMBL19102522 0.77 ALDH1A1 (0.41) ALDH1A1TSHRCA12CA2CA9
SCHEMBL10174084 0.77 ALDH1A1 (0.41) ALDH1A1NPC1LMNAGAARAB9A
SCHEMBL15966239 0.77 ALDH1A1 (0.41) ALDH1A1LMNAGAAL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765305-A4 CONTROLLED PHASE COMPOSITION TECHNOLOGY AS AN IMPROVED PROCESS FOR PROTECTION OF DRUGS DRUGTECH CORP (US) 2008-06-04 EP claimed
EP-0758244-B2 CONTROLLED-RELEASE DOSAGE FORMS OF AZITHROMYCIN PFIZER (US) 2008-02-13 EP claimed
EP-1765305-A1 CONTROLLED PHASE COMPOSITION TECHNOLOGY AS AN IMPROVED PROCESS FOR PROTECTION OF DRUGS Drugtech Corporation (US) 2007-03-28 EP claimed
WO-2006017159-A1 CONTROLLED PHASE COMPOSITION TECHNOLOGY AS AN IMPROVED PROCESS FOR PROTECTION OF DRUGS DRUGTECH CORPORATION (US) 2006-02-16 WO claimed
US-20060008527-A1 Controlled phase composition technology as an improved process for protection of drugs PARTICLE DYNAMICS INTERNATIONAL, LLC 2006-01-12 US claimed
US-20020044965-A1 Controlled- release dosage forms of azithromycin CURATOLO WILLIAM J (US) 2002-04-18 US claimed
EP-0758244-B1 CONTROLLED-RELEASE DOSAGE FORMS OF AZITHROMYCIN PFIZER (US) 2001-11-28 EP claimed
US-6068859-A AZITHROMYCIN AND A CARRIER WHICH RELEASES AZITHROMYCIN AT SPECIFIC DOSAGES AFTER TIME INTERVALS AFTER INGESTION; SIDE EFFECT REDUCTION PFIZER INC. (US) 2000-05-30 US claimed
EP-0758244-A1 CONTROLLED-RELEASE DOSAGE FORMS OF AZITHROMYCIN PFIZER INC. (US) 1997-02-19 EP claimed
WO-1995030422-A1 CONTROLLED-RELEASE DOSAGE FORMS OF AZITHROMYCIN PFIZER INC. (US) 1995-11-16 WO claimed
US-5032572-A Drug delivery MEDICAL COLLEGE OF OHIO (US) 1991-07-16 US claimed
US-4931432-A Dietary vaccine for inhibiting metabolism of methanol MONTE WOODROW C (US) 1990-06-05 US claimed
US-4834981-A Dietary vaccine for inhibiting metabolism of methanol MONTE WOODROW C (US) 1989-05-30 US claimed
US-4663308-A Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract MEDICAL COLLEGE OF OHIO (US) 1987-05-05 US claimed
US-12091428-B1 Chemoselective hydrogenation of α,β-unsaturated ketone and polyelectrochromism of electronically weakly coupled 4,4′-divinylazoarylene-bridged diruthenium complex bearing two Ru(CO)(2-hydroxyquinolato(PiPr3)2 moieties King Faisal University (SA) 2024-09-17 US disclosed
US-11986810-B1 Selective reduction catalyst of α,β-unsaturated ketone using electronically weakly coupled 4,4′-divinylazoarylene-bridged diruthenium complex bearing two Ru(CO)(8-mercaptoquinolato(PiPr3)2 moieties King Faisal University (SA) 2024-05-21 US disclosed
US-11987596-B1 Polyelectrochromism of electronically weakly coupled 4,4′-divinylazoarylene-bridged two Ru(CO)Cl(PiPr3)2 entities King Faisal University (SA) 2024-05-21 US disclosed
US-4834981-A Dietary vaccine for inhibiting metabolism of methanol MONTE WOODROW C (US) 1989-05-30 US disclosed
US-4663308-A Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract MEDICAL COLLEGE OF OHIO (US) 1987-05-05 US disclosed
US-4663308-A Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract MEDICAL COLLEGE OF OHIO (US) 1987-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12091428-B1 Chemoselective hydrogenation of α,β-unsaturated ketone and polyelectrochromism of electronically weakly coupled 4,4′-divinylazoarylene-bridged diruthenium complex bearing two Ru(CO)(2-hydroxyquinolato(PiPr3)2 moieties DHCR24, PI4K2A, PIP4K2A ALDH1A1 2799/4885NPC1 4307/4885MEN1 4127/4885
US-11987596-B1 Polyelectrochromism of electronically weakly coupled 4,4′-divinylazoarylene-bridged two Ru(CO)Cl(PiPr3)2 entities BICRA, LIG3, PIP4K2A ALDH1A1 4143/4885NPC1 4693/4885MEN1 2486/4885
US-11986810-B1 Selective reduction catalyst of α,β-unsaturated ketone using electronically weakly coupled 4,4′-divinylazoarylene-bridged diruthenium complex bearing two Ru(CO)(8-mercaptoquinolato(PiPr3)2 moieties PI4K2B, DHCR24, PI4K2A ALDH1A1 1919/4885NPC1 3451/4885MEN1 4233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.