Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 14/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17789661 | 0.92 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL17789663 | 0.91 | RAD52 (0.37) | NR1H4RAD52 | |
| SCHEMBL22626505 | 0.89 | NR1H4 (0.38) | NR1H4RAD52 | |
| SCHEMBL16377775 | 0.87 | RAD52 (0.36) | NR1H4RAD52 | |
| SCHEMBL17789665 | 0.87 | NR1H4 (0.30) | NR1H4 | |
| SCHEMBL22626243 | 0.87 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL16377948 | 0.87 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL17789657 | 0.86 | — | — | |
| SCHEMBL16377938 | 0.86 | RAD52 (0.35) | NR1H4RAD52 | |
| SCHEMBL17789646 | 0.85 | NR1H4 (0.31) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152626-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152626-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | FSHR, GNRHR, LHCGR | NR1H4 857/4885RAD52 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.