⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28239097 | 0.74 | — | — | |
| SCHEMBL27917455 | 0.72 | — | — | |
| SCHEMBL9719531 | 0.72 | — | — | |
| SCHEMBL2455472 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL8473221 | 0.69 | — | — | |
| SCHEMBL202989 | 0.67 | — | — | |
| SCHEMBL9805417 | 0.67 | — | — | |
| SCHEMBL11119228 | 0.64 | ALDH1A1 (0.31) | — | |
| SCHEMBL11048189 | 0.64 | — | — | |
| SCHEMBL6338979 | 0.64 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260020-B1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES B | NOVARTIS AG (CH) | 2014-07-23 | — | — | EP | disclosed |
| EP-2628726-A1 | Hydroxamate-based inhibitors of deacetylases b | Novartis AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| CN-102036955-B | Hydroxamate-based inhibitors of deacetylase B | NOVARTIS AG | 2013-03-27 | — | — | CN | disclosed |
| US-8349883-B2 | Hydroxamate-based inhibitors of deacetylases B | NOVARTIS AG (CH) | 2013-01-08 | — | — | US | disclosed |
| US-8017635-B2 | Phenylalkyl substituted heteroaryl derivatives | FMC CORPORATION (US) | 2011-09-13 | — | — | US | disclosed |
| US-20110183964-A1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES B | NOVARTIS AG (CH) | 2011-07-28 | — | — | US | disclosed |
| US-7943652-B2 | Hydroxamate-based inhibitors of deacetylases B | NOVARTIS AG (CH) | 2011-05-17 | — | — | US | disclosed |
| EP-2260020-A1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES B | Novartis AG (CH) | 2010-12-15 | — | — | EP | disclosed |
| EP-2204365-A1 | ALKYLSULFONE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-07-07 | — | — | EP | disclosed |
| US-20100168136-A1 | ALKYLSULFONE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-1119534-A1 | METHOD FOR THE PREPARATION OF 3-BROMO-1,1,1-TRIFLUOROPROPANE | GREAT LAKES CHEMICAL CORPORATION (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020362-A1 | METHOD FOR THE PREPARATION OF 3-BROMO-1,1,1-TRIFLUOROPROPANE | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-04-13 | — | — | WO | disclosed |
| US-5962754-A | CATALYTIC BROMINATION OF 3,3,,3-TRIFLUOROPROPENE | GREAT LAKES CHEMICAL CORPORATION (US) | 1999-10-05 | — | — | US | disclosed |
| US-4465786-A | CALCIUM OXYFLUORIDE CATALYST | GENERAL ELECTRIC COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0011738-B1 | PROCESS FOR LOWERING THE POROSITY AND SURFACE ROUGHNESS OF A CERAMIC SUPPORT AND COATING COMPOSITION THEREFOR | International Business Machines Corporation (US) | 1982-10-20 | — | — | EP | disclosed |
| US-4230773-A | Decreasing the porosity and surface roughness of ceramic substrates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| EP-0011738-A1 | Process for lowering the porosity and surface roughness of a ceramic support and coating composition therefor | International Business Machines Corporation (US) | 1980-06-11 | — | — | EP | disclosed |
| US-4195596-A | Combustion of halogenated hydrocarbons | THE DOW CHEMICAL COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4125593-A | Combustion of halogenated hydrocarbons | THE DOW CHEMICAL COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4064286-A | RESISTANCE TO COLOR BLEACHING, CHALKING, IMPROVED GLOSS RETENTION | PPG INDUSTRIES, INC. (US) | 1977-12-20 | — | — | US | disclosed |