Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793424 | 0.95 | MEN1 (0.43) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL29199093 | 0.87 | MEN1 (0.43) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL17793440 | 0.86 | MEN1 (0.39) | MEN1KMT2APOLBPABPC1ALOX5 | |
| SCHEMBL17793420 | 0.86 | MEN1 (0.44) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL17793487 | 0.86 | MAPK1 (0.46) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL17793437 | 0.85 | MEN1 (0.38) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL29199103 | 0.84 | ALDH1A1 (0.46) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL29199095 | 0.84 | ALDH1A1 (0.45) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL29199099 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2APOLBPABPC1MAPK1 | |
| SCHEMBL29199104 | 0.82 | MAPK1 (0.43) | MEN1KMT2APOLBPABPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016086022-A2 | HETEROAROMATIC IMIDAZOLYL COMPOUNDS AND METHODS FOR TREATING CANCER | CHANNEL THERAPEUTICS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |