Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793667 | 0.93 | GBA1 (0.61) | CA1CA2MAPTLMNAMEN1 | |
| SCHEMBL17793673 | 0.87 | CA1 (0.63) | CA1CA2MAPTLMNAMEN1 | |
| SCHEMBL17793672 | 0.86 | GBA1 (0.54) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL17793668 | 0.85 | TP53 (0.58) | CA1CA2MAPTLMNAMEN1 | |
| SCHEMBL17793731 | 0.85 | MAPT (0.64) | CA1CA2MAPTLMNAMEN1 | |
| SCHEMBL17793675 | 0.84 | MAPT (0.63) | CA1CA2MAPTLMNAMEN1 | |
| SCHEMBL17793671 | 0.83 | GBA1 (0.51) | CA1CA2LMNATP53SMN1; SMN2 | |
| SCHEMBL28910541 | 0.83 | MAPT (0.58) | CA1CA2MAPTLMNAMEN1 | |
| SCHEMBL17793710 | 0.82 | KMT2A (0.61) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL17793722 | 0.82 | CA2 (0.56) | CA1CA2MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016082052-A1 | COMPOUNDS DERIVED FROM 2-PHENYL-2-FLUOROSULFONAMIDES, USED AS BUILDING BLOCKS IN ORGANIC SYNTHESIS, AND METHOD FOR THE PRODUCTION THEREOF | PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) | 2016-06-02 | — | — | WO | disclosed |