Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17790883 | 1.00 | CNR1 (0.43) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL17790864 | 0.89 | CNR1 (0.41) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL17790888 | 0.88 | CNR1 (0.45) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL17790862 | 0.88 | CNR1 (0.45) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL19328452 | 0.88 | CNR1 (0.45) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL19656727 | 0.84 | ALDH1A1 (0.36) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL19343064 | 0.84 | CNR1 (0.49) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL17793922 | 0.83 | CNR1 (0.48) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| Methane SCHEMBL19640570 | 0.83 | CNR1 (0.41) | CNR1ALDH1A1CNR2ALOX12FAAH | |
| SCHEMBL19640775 | 0.83 | CNR1 (0.41) | CNR1ALDH1A1CNR2ALOX12FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016086136-A1 | FATTY ACID CYSTEAMINE CONJUGATES OF CFTR MODULATORS AND THEIR USE IN TREATING MEDICAL DISORDERS | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |