Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31607215 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| Hydrochloric Acid SCHEMBL177643 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| Hydrochloric Acid SCHEMBL29649805 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| SCHEMBL27715023 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| SCHEMBL27513588 | 0.83 | GRM4 (0.49) | ALDH1A1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL9772809 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| SCHEMBL31151693 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| SCHEMBL202448 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| Hydrochloric Acid SCHEMBL1682029 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 | |
| SCHEMBL899382 | 0.81 | MAPT (0.59) | ALDH1A1MAPTL3MBTL1KDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656401-A | Method for preparing 4-chloropyridine-2-methyl formate serving as sorafenib key intermediate and suitable for industrial production | 江苏恒沛药物科技有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-105330600-B | A kind of preparation method of Rui Gefeini | 山东罗欣药业集团股份有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-105566215-B | A kind of Rui Gefeini preparation method | 沈阳药科大学 | 2018-02-16 | — | — | CN | claimed |
| CN-106543077-A | N, N ' disubstituted arylthiourea derivative and its synthetic method and application | 西安交通大学 | 2017-03-29 | — | — | CN | claimed |
| CN-104045598-B | Thiourea compounds containing arylamine structure, and preparation method and application thereof | 烟台大学 | 2017-02-15 | — | — | CN | claimed |
| CN-105566215-A | Preparation method of Stivarga | UNIV SHENYANG PHARMACEUTICAL | 2016-05-11 | — | — | CN | claimed |
| CN-105330600-A | Preparation method for Regorafenib hydrate | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2016-02-17 | — | — | CN | claimed |
| CN-104045598-A | Thiourea compounds containing arylamine structure, and preparation method and application thereof | UNIV YANTAI | 2014-09-17 | — | — | CN | claimed |
| CN-103319402-A | Diphenyl thiourea derivatives, preparation method and applications thereof | QILU PHARMACEUTICAL CO LTD | 2013-09-25 | — | — | CN | claimed |
| CN-102993093-A | N,N'-2-substitubted-diphenylthiourea compound, as well as preparation method and applications thereof | UNIV YANTAI | 2013-03-27 | — | — | CN | claimed |
| EP-2562159-A1 | PREPARATION METHOD OF FLUORO-SUBSTITUTED DEUTERATED DIPHENYLUREA | Suzhou Zelgen Biopharmaceutical Co., Ltd. (CN) | 2013-02-27 | — | — | EP | claimed |
| CN-101830847-B | Anticancer compound and preparation method thereof | NAN ZHANG | 2012-10-10 | — | — | CN | claimed |
| CN-102653522-A | Omega-carboxy-substituted diphenylthiourea compounds, and preparation method and application thereof | UNIV YANTAI | 2012-09-05 | — | — | CN | claimed |
| CN-102617458-A | Preparation method for anticancer compound | NAN ZHANG | 2012-08-01 | — | — | CN | claimed |
| CN-101830847-A | Anticancer compound and preparation method thereof | SUZHOU MAIDIXIAN MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2010-09-15 | — | — | CN | claimed |
| CN-101230037-A | Anticancer medicine compound and its synthesis method | NAN ZHANG (CN) | 2008-07-30 | — | — | CN | claimed |
| WO-2025091127-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2025-05-08 | — | — | WO | disclosed |
| CN-114213310-B | Indoline compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-23 | — | — | CN | disclosed |
| US-3944524-A | ORAL HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1976-03-16 | — | — | US | disclosed |
| US-3933830-A | FROM 4-(2-PYRIDYLAMIDOETHYL) PYRIDINES REDUCED WITH HYDROGEN AND A NOBLE METAL CATALYST | PFIZER INC. (US) | 1976-01-20 | — | — | US | disclosed |