SCHEMBL17796299

SCHEMBL17796299

C=Cc1ccccc1-c1cccc(C=C)c1C=C.C=Cc1ccccc1-c1ccccc1C=C

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.33
NFE2L2 Q16236 1/20 0.30
ATR Q13535 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8848264 1.00 ALDH1A1 (0.43) ALDH1A1TSHRNFE2L2ATR
SCHEMBL4288834 0.93 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL132630 0.85 ALDH1A1 (0.55) ALDH1A1TSHRNFE2L2ATR
SCHEMBL29155309 0.84 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL7107668 0.83 ALDH1A1 (0.52) ALDH1A1TSHRNFE2L2ATR
SCHEMBL132631 0.83 ALDH1A1 (0.40) ALDH1A1TSHRATR
SCHEMBL8440886 0.80 ALDH1A1 (0.50) ALDH1A1TSHRNFE2L2
SCHEMBL18301 0.80 ALDH1A1 (0.48) ALDH1A1TSHRNFE2L2
SCHEMBL28593309 0.78 ALDH1A1 (0.41) ALDH1A1TSHRATR
SCHEMBL4807805 0.78 MYC (0.45) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029123-B1 PRODUCTION METHOD FOR PHOTOCHROMIC OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2019-09-18 EP disclosed
EP-3029123-A1 PRODUCTION METHOD FOR PHOTOCHROMIC OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2016-06-08 EP disclosed