SCHEMBL17797137

SCHEMBL17797137

CN(OCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
CA12 O43570 6/20 0.43
CA1 P00915 6/20 0.43
CA2 P00918 6/20 0.43
CA9 Q16790 6/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
IDO1 P14902 1/20 0.41
EPHX1 P07099 1/20 0.40
MALT1 Q9UDY8 1/20 0.38
CA14 Q9ULX7 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NQO2 P16083 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886873 0.92 TDP1 (0.46) TDP1MEN1GAAKMT2ACA12
SCHEMBL8305267 0.80 TDP1 (0.39) TDP1MEN1GAAKMT2ACA12
SCHEMBL20485175 0.78 MEN1 (0.44) TDP1MEN1GAAKMT2ACA12
SCHEMBL24290892 0.77 CA14 (0.35) CA12CA1CA2CA14
SCHEMBL27252284 0.77 HDAC6 (0.39) TDP1CA14
SCHEMBL12142888 0.77 TDP1 (0.40) TDP1MEN1GAAKMT2ACA12
SCHEMBL13055393 0.76 TDP1 (0.58) TDP1MEN1GAAKMT2ACA12
SCHEMBL3574542 0.76 TDP1 (0.50) TDP1MEN1GAAKMT2ACA12
SCHEMBL3341020 0.75 TDP1 (0.67) TDP1MEN1GAAKMT2ACA12
SCHEMBL26663588 0.75 HDAC6 (0.34) CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3028711-A1 Molecular building blocks capable of assembling carbohydrate derivatives, fatty acid residues and peptides Gubra ApS (DK) 2016-06-08 EP disclosed
EP-3028711-A1 Molecular building blocks capable of assembling carbohydrate derivatives, fatty acid residues and peptides Gubra ApS (DK) 2016-06-08 EP disclosed