Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | CA1 | P00915 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | CA9 | Q16790 | 7/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13792126 | 1.00 | TDP1 (0.39) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL17797137 | 0.80 | TDP1 (0.47) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL3886873 | 0.79 | TDP1 (0.46) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL8193597 | 0.77 | CTSK (0.33) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL8193600 | 0.77 | CTSK (0.33) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL19465020 | 0.77 | CTSK (0.33) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL24669520 | 0.75 | CA1 (0.36) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL24670538 | 0.74 | CA12 (0.31) | TDP1CA12CA1 | |
| SCHEMBL16808277 | 0.73 | CA12 (0.30) | CA12CA1 | |
| SCHEMBL7038864 | 0.73 | CA12 (0.30) | CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004091613-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |