Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.63 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.63 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797407 | 0.91 | S1PR1 (0.71) | S1PR1S1PR3 | |
| SCHEMBL9996209 | 0.91 | S1PR1 (0.77) | S1PR1S1PR3 | |
| SCHEMBL15703888 | 0.89 | S1PR1 (0.61) | S1PR1S1PR3S1PR5 | |
| SCHEMBL9996166 | 0.88 | S1PR1 (0.81) | S1PR1S1PR3 | |
| SCHEMBL17797406 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3S1PR5 | |
| SCHEMBL17805162 | 0.85 | S1PR1 (0.62) | S1PR1S1PR3 | |
| SCHEMBL177229 | 0.81 | S1PR1 (0.78) | S1PR1S1PR3 | |
| SCHEMBL9996208 | 0.81 | S1PR1 (0.86) | S1PR1S1PR3 | |
| SCHEMBL15497196 | 0.81 | S1PR1 (0.60) | S1PR1S1PR3 | |
| SCHEMBL15499276 | 0.80 | S1PR1 (0.66) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | claimed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |