Biphenyl

Biphenyl

SCHEMBL17798181

N#CN.O=C=NCN=C=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.36
TAAR1 Q96RJ0 3/20 0.34
TDP1 Q9NUW8 2/20 0.33
ADORA1 P30542 2/20 0.33
CYP3A4 P08684 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 3/20 0.33
MCL1 Q07820 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
MMP14 P50281 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL15542 0.89 ALDH1A1 (0.45) ALDH1A1TAAR1TDP1CYP3A4HSD17B10
Biphenyl SCHEMBL9561226 0.82 SMN1; SMN2 (0.40) ALDH1A1TAAR1KDM4EHPGDMEN1
Biphenyl SCHEMBL332251 0.78 ALDH1A1 (0.60) ALDH1A1TAAR1TDP1ADORA1CYP3A4
Biphenyl SCHEMBL2448212 0.76 ALDH1A1 (0.45) ALDH1A1TAAR1TDP1CYP3A4HSD17B10
Biphenyl SCHEMBL11588873 0.76 CYP3A4 (0.41) ALDH1A1TAAR1TDP1ADORA1CYP3A4
Biphenyl SCHEMBL11055825 0.75 ALDH1A1 (0.56) ALDH1A1TAAR1TDP1ADORA1CYP3A4
Benzene SCHEMBL21082728 0.75
Benzene SCHEMBL19066305 0.75
Benzene SCHEMBL740866 0.75
SCHEMBL454426 0.73 MEN1 (0.39) ALDH1A1TDP1CYP3A4HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160159967-A1 FUNCTIONAL POLYURETHANE FOAM HYUNDAI MOTOR COMPANY (KR) 2016-06-09 US claimed
CN-114787219-A Non-blended amphiphilic thermoplastic polyurethanes, methods of making the same, and implantable medical devices comprising the same 爱-森新株式会社 2022-07-22 CN disclosed
US-20160159967-A1 FUNCTIONAL POLYURETHANE FOAM HYUNDAI MOTOR COMPANY (KR) 2016-06-09 US disclosed
US-20160159967-A1 FUNCTIONAL POLYURETHANE FOAM HYUNDAI MOTOR COMPANY (KR) 2016-06-09 US disclosed