Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132453 | 0.80 | — | — | |
| SCHEMBL27145704 | 0.80 | CA1 (0.46) | — | |
| SCHEMBL6494607 | 0.79 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL6497775 | 0.76 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL30414514 | 0.76 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL6482890 | 0.76 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL12050694 | 0.75 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL4102536 | 0.75 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL4596643 | 0.75 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL14460704 | 0.75 | ALDH1A1 (0.58) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227297-A1 | 4,6-SUBSTITUTED-PYRAZOLO[1,5-a]PYRAZINES AS JANUS KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016090285-A1 | 4,6-SUBSTITUTED-PYRAZOLO[1,5-a]PYRAZINES AS JANUS KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-06-09 | — | — | WO | disclosed |